Hypertensive macro - and microangiopathy
Clinical symptoms and signs of hypertensive macroangiopathy mainly depend on what vessels are damaged. If the damage of lower limbs disturbed blood flow in the legs, pain, swelling. The common symptom is alternating lameness. When blockage of a blood clot may develop gangrene.
If damaged blood vessels of the brain, can develop conditions such as stroke, transient (passing) ischemic attack of the brain – short-term reversible stroke. Clinically the patient will lie such symptoms as impaired memory, headaches, dizziness, possible reversible focal manifestations in the form of a disorder, paresis.
In cardiac muscle macroangiopathy inevitably leads to the development of coronary heart disease. The person will feel pain behind the breastbone, between the shoulder blades with active exercise, shortness of breath. With the progression of the disease the tolerance of the loads is getting worse, the bouts of pain syndrome begin to appear spontaneously. An extreme manifestation of ischemic heart disease is acute myocardial infarction (heart muscle).
With the development of macroangiopathy of the kidneys deteriorating for most hypertension. May develop swelling, disruption of water and electrolyte metabolism, chronic renal failure.
Diagnosis and treatment
Hypertension diagnosis as a whole represents a comprehensive examination. It includes blood tests, monitoring of blood pressure, analysis of body response to the treatment. Detailed diagnosis of macroangiopathies determined by clinical symptoms. With the defeat of vessels of a brain and cervical MRI and ultrasound are used. Analysis of the heart and vascular health most of the heart muscle enable to assess the ECG, echocardiography, coronary angiography. Renal changes are estimated on the basis of ultrasound, intravenous urography, urine.
Tracking vascular changes important stage. The diagnosis adequately assessed violations of blood flow in a particular place of the body, depends on further treatment.
The fight against hypertension is aimed at continuous taking medications that reduce blood pressure numbers and reduce the risk of complications. Treatment of macroangiopathy must occur within the framework of the underlying disease. If in addition to high blood pressure there are changes in blood composition (increased lipid levels in the blood, a violation of their ratios, the increase in the viscosity and density of blood, required additional correctivestatin therapy and antiplatelet agents.
The treatment of such diseases as coronary heart disease, hypertension, microangiopathy and macroangiopathy is always complex, and should be aimed at breaking the pathological mechanisms of this pathology development.