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Isolated systolic hypertension and its treatment

Symptoms

The symptoms and course of ISAH often joined by symptoms of cerebral, coronary and renal disorders. High blood pressure contributes to the formation of complications in the heart, blood vessels, and mortality. Pulse pressure is an indicator of the biological age of the arteries.

Older people usually have a long clinical history. But at the same time, often with hypertension obvious symptoms of the disease is not very pronounced or even completely absent. Patients absolutely no complaints whatsoever, along with the diagnostically determined by the disruption of the heart, kidneys and brain.

There is a lot of cardiovascular (heart failure, stroke, heart attack) and metabolic (gout) complications. It is possible to increase total peripheral resistance of blood flow.

Meet about forms of the disease due to the increased stiffness of the vessels, the white coat hypertension (fear of doctors) or orthostatic (after head injury).

Features of treatment

Scientists have found that treatment of hypertension with antihypertensive therapy, may be minimized risk of complications and mortality.

At the beginning of treatment, doctors usually prescribe: Sartana, calcium antagonists, inhibitors of beta-blockers and ACE taking into account the General recommendations. When correctly selected therapy blood pressure should reach 140/90 mm Hg.St. and below. Proven efficacy of the complex treatment.

Vasoactive means of effectively reducing a tonus of arteries and increase their extensibility. Pressure decreases with decrease in ejection of blood from the left ventricle. With regular use diuretics reduce plasma volume and stroke volume of the heart.

For the prevention of complications and treatment of ISAH better take antihypertensive drugs of the first row. Even at long use they are not mass liquid, not breaking carbohydrate and lipid metabolism, does not provoke an orthostatic reaction and does not inhibit the activity of the Central nervous system.

Such medications include ACE inhibitors (ramipril, inapril, captopril, cilazapril), beta-blockers (bisoprol, atenolol, metoprolol, pindolol), tiazidove diuretics (hydrochlorothiazide) and calcium antagonists (amlodipine, isradipine, nifedipine, verapamil).

Elderly patients should be carefully selected dose with continuous blood pressure control. The measurement in this case is performed by standing up and not on an empty stomach. At the beginning of treatment blood pressure reduction should be gradual, approximately 30 % of the first indicators, so as not to cause kidney or brain failure. Continually monitor kidney function, carbohydrate and electrolyte metabolism.

European doctors often prescribe a combination of ACE inhibitor and hydrochlorothiazide, because they multiply the joint action and stimulate the natural compensatory feedback processes. At the same time inin almost any case prescribe drugs from two different groups. Thus reducing the risk of developing side effects.

Detailed examination of individual groups of drugs

Diuretics

This group of drugs prescribed for hypertension in almost all patients. Diuretics reduce stroke volume of the heart, the volume of circulating plasma, and improve the extensibility of the arteries. In combination with b-blockers to prevent coronary artery disease, cerebrovascular and overall mortality.