Fat embolism and its treatment

Accumulation of catecholamines - the main lipolytic agents. Violations of microcalorimetry and dysfunction of cell membranes cause brain swelling, toxic destruction of red blood cells, respiratory distress syndrome (ARDS), aplastic anemia, cardiac and renal failure.

Specific treatment for fat embolism is the full supply of oxygen to tissues. Holding the respirator when the disease is necessary when the impairment of consciousness of the patient in the form of excitation, mental inadequacy, somnolence or delirium. In these cases, the manipulation is performed even in the absence of symptoms of respiratory failure and acid-base balance shifts. In severe forms of fat embolism of the lung should be performed for a long time – until recovery of consciousness and lack of deterioration. At the time of transfer to independent breathing need to rely on indicators for monitoring the EEG.

Traumatic embolism administered disambiguator fat in the blood. Such drugs are deholin, LIPOSTABIL and Essentiale. Their impact is aimed at the renewal of the dissolution in the blood disambiguating fat. Helps the fat globules are to turn into a fine dispersion.

For the normalization of fibrinolysis and coagulation is used heparin. To appoint and to change the dosage doctor can. Often, the injuries, even if geparinoterapii develops DIC. Therefore in some cases produce a transfusion of fresh frozen plasma and fibrinolysin.

Fabrics must be protected from enzymes and free radicals. For this, prescribed corticosteroids (prednisone, dexamethasone). Noted that they stabilize the work of the blood-brain barrier, inhibit humoral cascades, restore membrane, improve the interpenetration of substances that prevent the development of pneumonia. It is also possible to use protease inhibitors and antioxidants.