Treatment of hypertension diuretics

Fast-acting diuretic

These drugs are used for first aid crew in the Ambulance, in the hospital. Are administered intravenously. For home use they are prescribed rarely. However, apart from the ampoule forms are available in tablets.

1. Lasix (Furosemide) — after intravenous administration the excretion of urine begins within 5 minutes of taking the tablet on an empty stomach increases this period to hours. Its effect does not last long (two hours after intravenous administration and 4-6 hours of ingestion, the concentration in the blood is reduced by half). Therefore, the drug gives an advantage to the use of other means of therapy. During this time, the patient is administered koronarolitiki, painkillers, sulphate of magnesia, spend the prevention of thrombosis in the vessels of the brain and heart.
2. Bumetanide (Burinex, Grinex) — begins to act half an hour later. Used in hypertension with renal insufficiency in severe congestive heart failure (swelling in the feet and legs).
3. The torasemid (Britomar, Diver) — works in only 15 minutes, but different from that of Furosemide more prolonged effect. Better saves potassium. Used in hypertension with chronic renal failure.
4. Uregyt (Ethacrynic acid) gives a strong diuretic effect, can be combined with Furosemide, because they have different points of application of the action. Duration from two to four hours. Not recommended in cases of oliguria or anuria (decrease or sudden cessation of urine output due to the blockade of the kidney), in the presence of hepatic insufficiency and diabetes mellitus in a patient. There is information about unwanted effects of the drug on hearing in long-term care.
5. Piretanide is a stronger diuretic than Furosemide. Able, in addition to diuretic action, lower blood clotting, widen the peripheral arteries. In the initial stage of hypertension is assigned for monotherapy, but is well compatible with other classes of drugs.

1. Triamterene (Pterofen, Daytek) — mild diuretic effect occurs within 3 hours and lasts up to 15 hours. More specifically, Verospiron. He that saves effect comes to the degree of hyperkalemia, especially in elderly patients). This contributes to the defeat of the renal tubules, the urine has a bluish tinge.
2. Amiloride (Midamor) — weak, but effective when combined with Furosemide, or Hydrochlorothiazide Uregita. Indicated in severe stages of hypertension in combination with heart failure.

A separate group of antagonists of aldosterone (the hormone that holds salt in the blood). Its representatives Veroshpiron (Spironolactone, Aldactone). They are not suitable for quick action by crises. The effect appears by the fifth day ingestion and lasts 2-3 days after cancellation. In full forcevalid only after 2 weeks. Because of corticosteroids has side effects in the type of body hair growth in women on the male type, in men, gynecomastia. Causes hormonal imbalance. It is therefore not recommended in endocrine pathology.

Rules for the treatment of hypertension diuretics

Given the pharmacodynamics of major drugs that doctors have to adhere to certain rules.

• Try not to apply or to nominate a very small dose for young patients, because the drugs, bringing water, contribute to blood products of metabolism, cholesterol, glucose. It contributes to the development of early atherosclerosis and diabetes.
• Treatment with diuretics is a complementary method and not eliminate the root cause of the disease. Therefore, they should be used in combination with other antihypertensives.
• In the absence of the diuretic effect is often the dosage is not increased and a diuretic added to another number.