Home / Medicines for the treatment of diseases of the cardiovascular system / A review of drug Corinfar (Corinfar)

A review of drug Corinfar (Corinfar)

Corinfar is a high degree of absorption up to 90%, the ability to be absorbed is between 50 and 70%. Food intake enhances the bioavailability.

Penetrate the drug through placental and blood-brain barrier, enters the breast milk. Undergoes complete metabolism in the liver.

The news is from 60 to 80% of the active substance in the bile – about 20%. The half-life is 2-5 hours.

Prolonged use of Corinfar (2-3 months) results in development of tolerance to the medication.

КоринфарThe drug "Corinfar" has a lot of side effects from various body systems.

The Central nervous system. Fatigue, weakness, dizziness, headache, drowsiness. Long-term use of the drug "Corinfar" may cause paresthesias (numbness) of extremities, tremors, Parkinsonian disorders (shuffling gait, impaired coordination of movements, mask-like face, tremors of hands and fingers), depression.

The cardiovascular system. Arrhythmia, tachycardia, palpitations, swelling (lower legs, ankles, feet), the development of heart failure, reducing AD, tides to a person of blood, a feeling of heat. Possible angina, and the development of heart attack (rare), in this case the drug needs to end.

Gastro-intestinal tract. Dry mouth, nausea, diarrhea or constipation, flatulence, increased appetite. Long-term use of pills "Corinfar" can lead to disruption in the functioning of the liver.

Musculoskeletal system. Swollen joints, arthritis, myalgia, spasms of the hands and feet.

The organs of hematopoiesis. Leukopenia, anemia, thrombocytopenia, agranulocytosis, thrombocytopenic purpura.

Urinary system. Increase in daily volume of urine, the kidneys with kidney failure.

Allergies. Urticaria, pruritus, dermatitis, skin rashes.

How to take?

The drug "Corinfar" taken orally, with liquid squeezed enough with plenty of water. It is recommended to take pills after a meal. When taking the drug with food increases absorption of the drug from the gastrointestinal tract but does not decrease the amount.

Scheme receiving Corinfar drug, dosage, duration of treatment depends on the diagnosis, severity of illness, patient's response to the action of the active substances and are determined only by the attending physician individually.

Overdose

In case of overdose may experience headache, tachycardia or bradycardia, decreases pressure, red face, developing bradiaritmia. In severe cases, loss of consciousness or onset of coma. In cases of poisoning by the drug "Corinfar" gastric lavage is recommended, in some cases, and small intestine.

Specific recommendations

Duringof the reception facilities "Corinfar" you cannot drink alcoholic beverages. Elimination of the drug occurs gradually. Taking the pill, you need to be careful when operating machinery, while driving and in any activity requiring your full attention.

Analogues

The most well-known analogues of the drug: Kordufan, adalat, Cordaflex, Cordipin, Fenigidin, Nifecard, Nifedipine, Confiden. They are composed of the same active substance – nifedipine.